C-8A-Oxo-avermectin and milbemycin derivatives, pharmaceutical compositions and method of use
US4547491A · kind A · utility
13Cited by
5References
18Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 18, 1984 |
| Grant date | Oct 15, 1985 |
| Priority date | — |
| Expiry date | Jul 18, 2004 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P33/00
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
There are disclosed novel avermectin and milbemycin compounds wherein the 8a position is oxidized to a ketone group. The 8a-oxo compounds are prepared by oxidizing an avermectin or milbemycin compound. The avermectin and milbemycin 8a-oxo compounds have utility as anti-parasitic agents and compositions for that use are also disclosed. The compounds are also highly potent insecticides against agricultural pests.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.