1,5-Benzothiazepines with cardiovascular utility, and pharmaceutical compositions containing them
US4547495A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jul 9, 1984 |
| Grant date | Oct 15, 1985 |
| Priority date | — |
| Expiry date | Jul 9, 2004 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P9/10
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
New 1,5-benzothiazepines of the following general formula ##STR1## wherein: R.sub.1 represents (C.sub.1-4)alkyl, (C.sub.1-4)alkoxy or a halogen atom; PA1 R.sub.2 is selected from: benzoyl independently substituted with 1 to 3 (C.sub.1-4)alkyl or (C.sub.1-4)alkoxy groups, or with halogen atoms; phenylcarbamoyl; phenylcarbamoyl independently substituted with 1 to 3 (C.sub.1-4) alkyl or (C.sub.1-4) alkoxy groups or with halogen atoms; the groups R.sub.5 -CO, in which R.sub.5 is the radical deriving from a heterocyclic ring optionally substituted by a (C.sub.1-4)alkyl or a (C.sub.1-4)alkoxy radical, or by a halogen atom; PA1 R.sub.3 and R.sub.4 independently represent (C.sub.1-4)alkyl groups; and salts therewith of pharmaceutically acceptable acids. The compounds of the invention possess cardiovascular utility.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.