Antibacterial agents
US4548815A · kind A · utility
3Cited by
0References
48Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 3, 1983 |
| Grant date | Oct 22, 1985 |
| Priority date | — |
| Expiry date | Oct 3, 2003 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D503/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The compounds of the formula (II): ##STR1## and salts and esters thereof wherein R is an inert ogranic group of up to 18 carbon atoms and are able to inhibit the action of various bacterial .beta.-lactamases. Thus when a compound of the formula (II) or its salt or ester is used together with a penicillin or cephalosporin, the effectiveness of that penicillin or cephalosporin can be considerably enhanced. These novel synergysts can be prepared by etherification of an ester of clavulanic acid followed if desired by deesterification. The novel synergysts also possess antibacterial activity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.