Guanidino-heterocyclyl-phenyl-amidines and salts thereof
US4548944A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Feb 10, 1983 |
| Grant date | Oct 22, 1985 |
| Priority date | — |
| Expiry date | Feb 10, 2003 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07F9/5463
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Compounds of the tautomeric formula ##STR1## wherein R, R.sub.1 and R.sub.2, which may be identical to or different from each other, are each hydrogen or alkyl of 1 to 4 carbon atoms; PA1 R.sub.3 is straight or branched alkyl, optionally interrupted by heteroatoms such as oxygen, sulfur or nitrogen; straight or branched alkenyl; alkynyl; cyano; cycloalkyl or cycloaliphatic alkyl; a bicyclic group; aryl; or a heterocyclic group; or PA1 R.sub.2 and R.sub.3, together with each other and the nitrogen atoms to which they are attached, form a heterocyclic group; PA1 R.sub.4 is hydrogen, halogen, alkyl of 1 to 4 carbon atoms or alkoxy of 1 to 4 carbon atoms; and PA1 Het is a substituted or unsubstituted heterocycle containing two or three heteroatoms; tautomers thereof, and non-toxic, pharmacologically acceptable acid addition salts thereof. The compounds as well as their salts are useful as anti-ulcerogenics.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.