Patent · US Expired

Lipoidal biopterin compounds

US4550109A · kind A · utility

88Cited by
1References
7Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMay 31, 1984
Grant dateOct 29, 1985
Priority date
Expiry dateMay 31, 2004

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61P25/00
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

The present invention provides lipoidal biopterin and tetrahydrobiopterin compounds of the general structure: ##STR1## wherein --R is absent when ring B has two double bonds, PA0 --R is hydrogen when the two double bonds in ring B are absent, and PA0 --R' and R" are selected from saturated or unsaturated, cyclic or non-cyclic hydrocarbons of 1 to 31 carbon units. The compounds provided by this invention are oil soluble and can readily be formulated as an oil based pharmaceutical useful for the treatment of phenylketonuria, Parkinsonism, depression, senile dementia, Alzheimer's disease and related biopterin deficiency diseases.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.