6-(1,8-Naphthyridin-2-yl)-dithiino[1,4][2,3-c]-pyrroles useful as tranquillizers and anticonvulsants

US4550110A · kind A · utility

Assignee

• Rhone-Poulenc Sante · FR

Inventors

• Daniel Farge · Thiais, FR
• Andre Leger · Paris, FR
• Gerard Ponsinet · Sucy-en-Brie, FR

Key dates

• Filing date: Apr 21, 1983
• Grant date: Oct 29, 1985
• Expiry date: Apr 21, 2003

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P25/20
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

New compounds of the formula ##STR1## wherein X represents hydrogen, halogen, alkyl (1 to 4 C), alkoxy (1 to 4 C), cyano or nitro, R represents hydrogen, alkyl (1 to 4 C) [unsubstituted or substituted by 1, 2 or 3 halogens, alkenyl (2 to 4 C), alkynyl (2 to 4 C) or alkoxy (1 to 4 C)], phenyl [unsubstituted or substituted by 1, 2 or 3 halogens, alkyl (1 to 4 C), alkoxy (1 to 4 C), nitro or trifluoromethyl] or phenylalkyl (1 to 4 C) or phenylalkynyl (2 to 4 C) in which the phenyl radicals are optionally substituted as indicated above, Z represents an oxygen or sulphur atom, and one of m and p represents the figure O and the other the figure 1. The new compounds are therapeutically useful, more particularly as tranquillizers and anticonvulsants.