Patent · US Expired

Tricyclic derivatives of 5,6-dihydro-11H-dibenzo (b,e) azepin-6-one having pharmacological activity

US4551451A · kind A · utility

1Cited by
2References
18Claims
0Family size

Assignee

Inventors

Key dates

Filing dateAug 10, 1984
Grant dateNov 5, 1985
Priority date
Expiry dateAug 10, 2004

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61P25/20
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

A pharmacologically active compound has the general formula ##STR1## in which R is a hydrogen atom or an alkyl group containing from 1 to 4 carbon atoms; R.sub.1 and R.sub.2, which can be different, represent a hydrogen atom, a hydroxyl group, an alkyl group, an alkoxy group, an arylalkyl group, or an arylalkoxy group, or can jointly represent an oxygen atom or a CHCOOR.sub.1 ' group where R.sub.1 ' is a hydrogen atom or an alkyl group; and R.sub.3 represents a hydrogen or halogen atom or an alkyl, NH.sub.2, NO.sub.2, NHCO-alkyl, NHCO-aryl, NHCONH-alkyl or NHCOHN-aryl group. These compounds act on the central nervous system and have an anti-convulsant sedative activity.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.