Use of 3-indolepyruvic acid for increasing serotonin
US4551471A · kind A · utility
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Key dates
| Filing date | Oct 7, 1983 |
| Grant date | Nov 5, 1985 |
| Priority date | — |
| Expiry date | Oct 7, 2003 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02P20/582
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The process for the biosynthesis of 3-indolpyruvic acid involves the reaction of tryptophan with purified enzyme aspartate aminotransferase obtained from the mytochondria of slaughterhouse animals. When administered orally in rats, 3-indolpyruvic acid leads to a considerable increase in cerebral serotonin levels, and so may be used in all the pathological conditions of the central nervous system involving deficiencies of this neurotransmitter, such as depressions, insomnia, lack of appetite, neuroendocrin imbalances, etc.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.