Patent · US Expired

N.sub.b Quaternary derivatives of ajmaline and isoajmaline, methods and intermediate products in the manufacture of their derivatives and method of using same and pharmaceutical compositions thereof

US4554274A · kind A · utility

0Cited by

0References

8Claims

0Family size

Assignee

Kali-Chemie Pharma GmbH · DE

Inventors

Wolfgang Kehrbach · Hannover, DE
Joachim Wegener
Ulrich Kuehl · Hannover, DE
Renke Budden · Hannover, DE
Gerd Buschmann · Velbert, DE

Key dates

Filing date	May 31, 1984
Grant date	Nov 19, 1985
Priority date	—
Expiry date	May 31, 2004

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61P9/06
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

New quaternary derivatives of 10-bromoajmaline and 10-bromoisoajmaline are disclosed which exhibit antiarrhythmic and adrenolytic properties and which have the formula I ##STR1## wherein R represents a carbon-attached organic group containing 1 to 10 carbon atoms and A.sup.- represents an acid anion as well as pharmaceutical formulations thereof and processes and intermediates for their preparation.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.