Patent · US Expired

Composition, analytical element and method for the detection of bacteria

US4556636A · kind A · utility

43Cited by
10References
25Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJun 9, 1983
Grant dateDec 3, 1985
Priority date
Expiry dateJun 9, 2003

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12Q1/04
  • WIPO fieldBasic materials chemistry
  • WIPO sectorChemistry

Abstract

A composition, an analytical element and a method for the detection of bacteria in specimen samples, e.g. biological fluids, are disclosed. The composition optionally, but preferably, comprises a metabolizable substrate (e.g. glucose) and a benzindole dye which undergoes a detectable color change when incubated in admixture with a bacterial microorganism. Useful dyes include particular benz[cd]indole, benz[e]indole and benz[g]indole compounds. The described analytical element contains this composition, preferably, in a spreading zone. Detection of bacteria can be accomplished by bringing the composition or element into contact with a specimen sample. This invention is particularly useful in detection of significant bacteriuria.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.