Penetrating topical pharmaceutical compositions containing 1-dodecyl-azacycloheptan-2-one
US4557934A · kind A · utility
197Cited by
20References
23Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Jun 21, 1983 |
| Grant date | Dec 10, 1985 |
| Priority date | — |
| Expiry date | Jun 21, 2003 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K31/57
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Improved topical pharmaceutical compositions containing a pharmaceutically-active agent and the penetration enhancing agent 1-dodecylazacycloheptan-2-one are disclosed. This agent is used at selected levels in combination with certain C.sub.3 -C.sub.4 diols or a 1-substituted azacycloalkyl-2-one. This composition provides marked transepidermal and percutaneous delivery of the selected pharmaceutically-active agent. A method of treating certain pathologies and conditions responsive to the selected active, systemically or locally, is also disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.