Patent · US Expired

Antiandrogenic 17.alpha.-substituted steroids

US4558041A · kind A · utility

6Cited by

2References

8Claims

0Family size

Assignee

SCHERING CORPORATION · US

Inventors

Rudolf Wiechert · Berlin, DE
Dieter Bittler · Berlin, DE
Annerose Schleusener · Berlin, DE
Manfred Albring · Berlin, DE

Key dates

Filing date	Jun 13, 1984
Grant date	Dec 10, 1985
Priority date	—
Expiry date	Jun 13, 2004

Classification

Technology area (CPC Y)Emerging Cross-Sectional Technologies
CPC primaryY02P20/55
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

17.alpha.-substituted steroids of the formula ##STR1## wherein R.sub.1 is hydrogen, acyl, alkyl, alkenyl, alkyl or alkenyl interrupted by an oxygen atom, cyclopentyl, or tetrahydropyranyl, PA1 R.sub.2 is alkyl or alkenyl of 2-6 carbon atoms, PA1 X is oxygen or the grouping H(OR.sub.3) wherein R.sub.3 is hydrogen, acyl, alkyl, alkenyl, alkyl or alkenyl interrupted by an oxygen atom, cyclopentyl, or tetrahydropyranyl, upon topical application, display antiandrogenic properties and can be utilized for the treatment of acne, seborrhea, alopecia and hirsutism.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.