Polyamine based bonded phase chromatography
US4560704A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Nov 12, 1982 |
| Grant date | Dec 24, 1985 |
| Priority date | — |
| Expiry date | Nov 12, 2002 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB01J20/3272
- WIPO fieldChemical engineering
- WIPO sectorChemistry
Abstract
Bonded phase chromatography is disclosed wherein an organosilane reacts with a polyamine to form a support matrix which is attached to the inorganic surface of a support structure. In forming an organic polyamine support matrix, a neutral organosilane is bonded to the inorganic surface with the organosilane having a functional group sufficiently reactive so that an organic amine polymer reacts with the functional group to cause covalent bonding of the organic amine polymer to the inorganic surface. By addition of an organic stationary phase group, the organic polyamine support matrix is formed into any predetermined one of a plurality of types of chromatography supports.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.