Patent · US Expired

Glass-surface microcarrier for anchorage-dependent cell cultivation

US4564532A · kind A · utility

13Cited by
5References
7Claims
0Family size

Assignee

Inventor

Key dates

Filing dateJan 7, 1985
Grant dateJan 14, 1986
Priority date
Expiry dateJan 7, 2005

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12N2533/12
  • WIPO fieldSurface technology, coating
  • WIPO sectorChemistry

Abstract

A chemical vapor deposition process for making glass-surfaced microcarriers, and the resulting product, in which hollow spherical micro-sized shells of glass or ceramic composition are placed within a fluidized bed coater, and separate preheated reaction gasses are directed into the coater bed. The shell precursors have a preferred starting density of not more than the predetermined desired final density in the range of 1.01 to 1.2 g/cc, and have a diameter in the range of 5 to 500 .mu.m, preferably 105 to 150 .mu.m. The thickness of the silicate glass coating is preferably in the range of 11 to 16 .mu.m. An alternative embodiment employs solid precursor beads of polyphenylene oxide.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.