Patent · US Expired

Preparation of 17.beta.-hydroxyacetyl-17.alpha.-ol-steroids

US4565656A · kind A · utility

4Cited by
3References
9Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJan 27, 1982
Grant dateJan 21, 1986
Priority date
Expiry dateJan 27, 2002

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07J5/0053
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

A novel process for the preparation of 17.beta.-hydroxyacetyl-17.alpha.-ol-steroids of the formula ##STR1## wherein R.sub.1 is selected from the group consisting of hydrogen, alkyl of 1 to 4 carbon atoms optionally substituted with halogen or an oxygen or nitrogen function and alkenyl and alkynyl of 2 to 4 carbon atoms, R.sub.2 is alkyl of 1 to 4 carbon atoms and the A,B,C and D rings may contain one or more double bonds and are optionally substituted with at least one member of the group consisting of hydroxy, keto, halogen, alkyl and alkoxy of 1 to 4 carbon atoms and alkenyl and alkynyl of 2 to 4 carbon atoms which compounds are generally known of the cortisonic type with known properties.

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