Binding assay system and method of making and using same
US4567149A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Mar 17, 1983 |
| Grant date | Jan 28, 1986 |
| Priority date | — |
| Expiry date | Mar 17, 2003 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2035/1062
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Method and apparatus for use in the diagnostic analysis of a liquid specimen through binding assays. The apparatus includes a rigid body having an elongated, shallow well formed in it, with a plurality of elongated strips, preferably in the form of cotton threads, stretched across the well in spaced relationship and generally perpendicular to the well's longitudinal axis. Each thread is coated with a separate binding conjugate such as an antigen or allergen. A cover plate that includes a thin plastic layer and an overlaying thin metallic layer covers the well to form an enclosed chamber having a specific volume. The metallic layer includes a separate elongated aperture in alignment with each coated thread. A liquid specimen is introduced into the chamber through one of two ports, for incubation with the coated threads, after which the specimen is removed and the reaction that occurred on each thread is determined.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.