6.alpha.-Methylprednisolone derivatives
US4567172A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | May 27, 1983 |
| Grant date | Jan 28, 1986 |
| Priority date | — |
| Expiry date | May 27, 2003 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07J31/006
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A 6.alpha.-methylprednisolone derivative of the general formula: ##STR1## wherein R.sup.1 is a hydrogen atom or stands for the grouping ##STR2## where R.sup.3 is a straight or once-branched chain C.sub.1-4 alkyl group, a phenyl group or a lower alkoxy- or alkylthio-methyl group, and R.sup.2 is a straight or once-branched chain C.sub.1-4 alkyl group, a phenyl group or a lower alkoxy- or alkylthio-methyl group, with the proviso that when R.sup.2 is ethyl group, R.sup.1 should not be a hydrogen atom or R.sup.3 should not be ethyl group. This compound exhibits a strong local antiinflammatory effect and is, therefore, useful as a harmless external antiinflammatory drug for various dermal disorders and also as an antiallergic drug for treating asthma and the like allergic diseases.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.