Ethanethioates and mercaptoamides and use thereof as analgesic and enkephalinase inhibitory compounds
US4567198A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Feb 6, 1984 |
| Grant date | Jan 28, 1986 |
| Priority date | — |
| Expiry date | Feb 6, 2004 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C327/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Novel analgesic and enkephalinase inhibiting compositions comprising an analgesically and enkephalinase inhibitory effective amount of at least one compound selected from the group consisting of a compound of the formula ##STR1## wherein R.sub.1 is selected from the group consisting of hydrogen and acetyl, n is 1 or 2 and when n is 1, R.sub.2 is selected from the group consisting of phenyl, p-chlorophenyl, m-trifluoromethylphenyl and thiazolyl and when n is 2, R.sub.2 is selected from the group consisting of phenyl and p-chlorophenyl and their salts with non-toxic, pharmaceutically acceptable acids and bases and an inert pharmaceutical carrier and novel method of relieving pain and inhibiting enkephalinase activity in warm-blooded animals and novel amides.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.