Patent · US Expired

Protein compounds

US4568665A · kind A · utility

6Cited by
3References
15Claims
0Family size

Inventor

Key dates

Filing dateJun 25, 1984
Grant dateFeb 4, 1986
Priority date
Expiry dateJun 25, 2004

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61K38/00
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention is directed to certain multiprotein compounds and methods for using such compounds in the treatment of cancer, psoriasis, arthritis, erythropoietic protoporphyria, and scar tissue and wounds. These multiprotein compounds include beta-lactoglobulin, alpha-lactalbumin, and bacitracin. The beta-lactoglobulin proteins are linked to alpha-lactalbumin proteins by a plurality of organic linkages formed by reacting various alcohols, e.g., noncyclic alcohols, steroid alcohols, triterpenoid alcohols, and thioglycerol therewith. The alpha-lactalbumin proteins are linked to the bacitracin proteins by a plurality of organic linkages formed by reacting with fatty acids therewith. A selenium ion may be bonded to each bacitracin protein molecule of the multiprotein compounds. Additionally, pairs of bacitracin molecules may be linked by zinc ions or other cations, to form a salt with the bacitracin.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.