Process for stabilizing aqueous solutions of acetoacetamides with simultaneous reduction in the content of .beta.-aminocrotonic acid amides
US4571433A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Sep 10, 1984 |
| Grant date | Feb 18, 1986 |
| Priority date | — |
| Expiry date | Sep 10, 2004 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C233/02
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A process for stabilizing aqueous solutions of acetoacetamides which simultaneously results in the reduction of .beta.-aminocrotonic acid amide content. According to the process, to aqueous acetoacetamide solutions which have been prepared in a known manner by the reaction of diketene with ammonia or water-soluble primary or secondary aliphatic amines under basic conditions, sufficient amounts of diketene are added immediately after their preparation thereto at room temperature with vigorous stirring, to maintain a pH value of 6-7. The so obtained aqueous solutions of the acetoacetamides are not only substantially stable, but also especially pure since these solutions are neither contaminated by salt-like by-products nor by derivatives of .beta.-aminocrotonic acid amides.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.