2-(Secondary aminoalkoxymethyl) dihydropyridine derivatives as anti-ischaemic and antihypertensive agents
US4572909A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Feb 3, 1984 |
| Grant date | Feb 25, 1986 |
| Priority date | — |
| Expiry date | Feb 3, 2004 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02P20/55
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A dihydropyridine compound of the formula ##STR1## or a pharmaceutically acceptable acid addition salt thereof, wherein PA0 Y is --(CH.sub.2).sub.2 --, --(CH.sub.2).sub.3 --, --CH.sub.2 CH(CH.sub.3)-- or --CH.sub.2 C(CH.sub.3).sub.2 --; PA0 R is aryl or heteroaryl; PA0 R.sup.1 and R.sup.2 are each independently C.sub.1 -C.sub.4 alkyl or 2-methoxyethyl; and PA0 R.sup.3 is hydrogen, C.sub.1 -C.sub.4 alkyl, 2-(C.sub.1 -C.sub.4 alkoxy)ethyl, cyclopropylmethyl, benzyl, or --(CH.sub.2).sub.m COR.sup.4 where m is 1, 2 or 3 and PA0 R.sup.4 is hydroxy, C.sub.1 -C.sub.4 alkoxy or --NR.sup.5 R.sup.6 where R.sup.5 and R.sup.6 are each independently hydrogen or C.sub.1 -C.sub.4 alkyl can be employed for treating or preventing a heart condition or hypertension.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.