Use of 3-(arylmethyleneamino)-1-aryl-2-pyrazolines in the prophylaxis and treatment of inflammation, pain, pyresis, and asthma
US4572913A · kind A · utility
0Cited by
0References
17Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 15, 1981 |
| Grant date | Feb 25, 1986 |
| Priority date | — |
| Expiry date | Dec 15, 2001 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D231/06
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Compounds of formula (I) ##STR1## inhibit both the cyclo-oxygenase and lipoxygenase pathways of arachidonic acid oxygenation and are useful in medicine as, e.g., anti-inflammatory and anti-asthmatic agents. The compounds may be administered as the raw chemical or in association with a carrier as a pharmaceutical formulation. The compounds may be prepared by methods analogous to those known in the art, e.g., by the method of Duffin and Kendall in J. Chem. Soc. (1954), 408-415, or by other methods.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.