4,4'-Alkylenedipiperidine derivatives
US4574123A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | May 3, 1984 |
| Grant date | Mar 4, 1986 |
| Priority date | — |
| Expiry date | May 3, 2004 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D211/16
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A 4,4'-alkylenebis[piperidine-1-(N-amidinoamidine)] derivative of the formula: ##STR1## or a tautomeric form thereof, wherein each of R.sup.1, R.sup.2, R.sup.3 and R.sup.4, which may be the same or different, is hydrogen or an alkyl, alkenyl or alkoxyalkyl radical of up to 20 carbon atoms; or R.sup.1, R.sup.2 and the nitrogen atom to which they are attached, or R.sup.3 and R.sup.4 and the nitrogen atom to which they are attached, which may be the same or different, are each a 1-azetidinyl, 1-pyrrolidinyl, piperidino, hexamethyleneimino, heptamethyleneimino, morpholino or 4-(1-8C alkanoyl)-1-piperazinyl radical each of which may bear 1-3C alkyl substituents; a 3-20C cycloalkyl radical; or an optionally substituted phenyl or phenylalkyl radical; provided that at least one of R.sup.1, R.sup.2, R.sup.3 and R.sup.4 is other than hydrogen; X is a direct bond or a 1-6C straight- or branched-chain alkylene radical which is linked to the 3- or 4-positions of the piperidine rings; and R.sup.5 and R.sup.6, which may be the same or different, are each hydrogen or a 1-8C alkyl radical; and the acid addition salts thereof, processes for their manufacture, and antibacterial and antifungal composi…
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.