Radio frequency-induced hyperthermia for tumor therapy
US4574782A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Nov 21, 1983 |
| Grant date | Mar 11, 1986 |
| Priority date | — |
| Expiry date | Nov 21, 2003 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61N1/406
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
This invention is directed to a method for reducing the mass of a tumor in animal tissue utilizing localized, magnetically-coupled, RF-induced hyperthermia. The method involves the implanting of a material in and/or closely adjacent to the tumor which is non-toxic to, and preferably inert to and compatible with, normal tissue and which has encapsulated therewithin ferromagnetic particles of such size, amount, composition, and ferromagnetism to develop a heating value of up to about one watt/gram, through essentially only hysteresis heating, under an applied field of about 20 but less than 200 oersteds at a frequency greater than 10 kilohertz and ranging up to about 600 kilohertz, or under an applied field of at least about 2000 oersteds and a frequency below about 40 hertz. Such heating value is sufficient to kill the tumor cells but muscle and nerve response of the animal body to the induced emf is minimized.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.