Process for the preparation of a biologically active extract
US4576696A · kind A · utility
Assignee
Inventor
Key dates
| Filing date | Sep 19, 1984 |
| Grant date | Mar 18, 1986 |
| Priority date | — |
| Expiry date | Sep 19, 2004 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K35/54
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A mammal organ, for example the thymus, or a cell culture is comminuted to form a slurry, accompanied by cell disintegration, high molecular weight substances are precipitated by heating and removed by centrifuging, and residual substances of molecular weight greater than 10,000 are separated out by ultrafiltration; finally, the salts are substantially removed by electrodialysis. A biologically active, low-salt, sterile, pyrogen-free and antigen-free complete extract is obtained and, in contrast to all known processes, no foreign substance or auxiliary, other than water--not even a preservative or a carrier for separation methods--is used.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.