Anti-rheumatic 5-(substituted amino)-1,2-dithiol-3-one compounds and their use
US4576954A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Feb 21, 1984 |
| Grant date | Mar 18, 1986 |
| Priority date | — |
| Expiry date | Feb 21, 2004 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D339/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
New derivatives of the general formula (I) in which: PA0 R=H or Cl and either R.sub.1 and R.sub.2 form a tetrahydroquinoxaline, tetrahydroquinoline, tetrahydroisoquinoline, dihydrobenzoxazine, tetrahydro-1H-benzazepine or isoindoline ring, it being possible for all these rings to be substituted by one or more halogen, carboxyl, alkoxycarbonyl, carbamoyl, alkylcarbamoyl, dialkylcarbamoyl, trifluoromethyl, cyano, nitro, alkoxy, alkylthio or alkyl, substituted by carboxyl, alkoxycarbonyl, carbamoyl, alkylcarbamoyl, dialkylcarbamoyl, hydroxyl, amino, alkylamino or dialkylamino, or R.sub.1 =alkyl and R.sub.2 =alkyl substituted by phenyl which is itself unsubstituted or substituted by one or more halogen, alkyl, alkoxy, alkylthio, hydroxy, amino, alkylamino, dialkylamino, carboxy, alkoxycarbonyl, carbamoyl, alkylcarbamoyl, dialkylcarbamoyl, trifluoromethyl, cyano or nitro, all the alkyls having 1 to 4 C in a straight or branched chain. These new products are used as antirheumatics. ##STR1##
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.