Patent · US Expired

Method and apparatus for sampling liquid phase components from a liquid-semisolid fluid

US4577514A · kind A · utility

87Cited by
9References
19Claims
0Family size

Assignee

Inventors

Key dates

Filing dateApr 9, 1984
Grant dateMar 25, 1986
Priority date
Expiry dateApr 9, 2004

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY10T436/25375
  • WIPO fieldMeasurement
  • WIPO sectorInstruments

Abstract

To sample liquid phase components of a biological fluid which has been subjected to centrifugation to separate its liquid and semisolid phase components and define a liquid-semisolid interface therebetween, a probe carrying a sensor at its end is extended into and through the liquid phase components until the sensor detects the interface, whereupon further extension of the probe into the fluid is halted. A sample of liquid phase components is then withdrawn through openings in the probe spaced from the interface, so that only liquid components are sampled. It is contemplated that a stopper close a vessel containing the biological fluid, and that the probe be extended through and movable within a needle which first pierces the stopper, so that the probe may be moved through the needle and into the vessel. It is also contemplated that the withdrawn liquid phase components be aseptically transferred to a receiving vessel, and that the probe be cleansed with a flushing solution between sampling operations.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.