Patent · US Expired

Di-enzymatic dentifrice

US4578265A · kind A · utility

35Cited by
8References
17Claims
0Family size

Assignee

Inventors

Key dates

Filing dateAug 13, 1981
Grant dateMar 25, 1986
Priority date
Expiry dateAug 13, 2001

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61K8/66
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

A di-enzymatic dentifrice is provided which contains an oxidizable substrate and an oxidoreductase enzyme specific to such substrate for producing hydrogen peroxide upon oral application of the dentifrice and further contains a thiocyanate salt and lactoperoxidase for interacting with hydrogen peroxide to produce a hypothiocyanate bacterial inhibitor. An illustrative enzymatic system for this purpose contains glucose, glucose oxidase, potassium thiocyanate and lactoperoxidase.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.