Pharmaceutical compositions containing insulin
US4579730A · kind A · utility
115Cited by
0References
4Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 9, 1984 |
| Grant date | Apr 1, 1986 |
| Priority date | — |
| Expiry date | May 9, 2004 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/55
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention provides a pharmaceutical composition for the oral administration of insulin comprising insulin, a bile acid or alkali metal salt thereof, the bile acid being selected from the group consisting of cholic acid, chenodeoxycholic acid, taurocholic acid, taurochenodeoxycholic acid, glycocholic acid, glycochenocholic acid, 3.beta.-hydroxy-12-ketocholic acid, 12.alpha.-3.beta.-dihydrocholic acid, and ursodesoxycholic acid, and a protease inhibitor, the composition being provided with an enterocoating to assure passage through the stomach and release in the intestine.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.