Patent · US Expired

Aryloxypropanolamine derivatives, pharmaceutical compositions and adrenegic thereof

US4579861A · kind A · utility

1Cited by
1References
9Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJan 6, 1984
Grant dateApr 1, 1986
Priority date—
Expiry dateJan 6, 2004

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D405/04
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Compounds having general formula I ##STR1## wherein R.sub.1 is hydrogen, lower alkyl, lower alkoxy, alkyl enoxy, halogen, cyano, carboxyamido or ureido group optionally separated from the phenyl ring by a methylene or ethylene bridge; PA1 R.sub.2 is hydrogen, halogen, lower alkyl or alkoxy; PA1 R.sub.3 is hydrogen, halogen, lower alkyl, lower alkoxy or R.sub.2 and R.sub.3, taken together, are a methylendioxy group; PA1 R.sub.4 is hydrogen or lower alkyl, endowed with remarkable cardioselective .beta.-adrenolytic properties, are described. The process for their preparation and pharmaceutical compositions containing them are also described.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.