Patent · US Expired

Intramolecularly cross-linked hemoglobin and method of preparation

US4584130A · kind A · utility

100Cited by
11References
42Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMar 29, 1985
Grant dateApr 22, 1986
Priority date
Expiry dateMar 29, 2005

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61K38/00
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Stroma-free hemoglobin cross-linked with reagents that mimic 2,3 diphosphoglycerate and transform stroma-free hemoglobin into a physiologically competent oxygen carrier which is retained in vivo for adequate periods of time and thus can be used in fluids for transporting oxygen; reagents for cross-linking stroma-free hemoglobin and method for cross-linking stroma-free hemoglobin.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.