Substituted pyrido (1,2-c)imidazo(1,2-a)benzimidazoles, processes for their preparation, their use and pharmaceutical preparations based on these compounds

US4585775A · kind A · utility

Assignee

• Hoechst GmbH · DE

Inventors

• Volker Hitzel · Hofheim, DE
• Gerhard Rackur · Idstein, DE
• Martin Bickel · Frankfurt am Main, DE

Key dates

• Filing date: Sep 13, 1984
• Grant date: Apr 29, 1986
• Expiry date: Sep 13, 2004

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y02P20/55
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The invention relates to compounds of the formula ##STR1## in which R.sup.1 and R.sup.2 are identical or different and are hydrogen, alkyl, trifluoromethyl, halogen, alkoxycarbonyl, alkoxy or alkanoyl, R.sup.3, R.sup.4 and R.sup.5 are identical or different and are hydrogen, methyl, alkoxy or alkoxyethoxy, and R is hydrogen or a group SR.sup.6, in which R.sup.6 is the lone, unpaired electron of the 12-sulfenyl radical, hydrogen, optionally substituted alkyl, alkenyl, alkynyl, alkanoyl, optionally mono- or poly-substituted benzoyl, fuoryl, phenacyl, phenoxyacetyl, phenylacetyl or another conventional thiol-protective group, and to physiologically acceptable salts thereof, and to processes for their preparation, to their use as a gastric acid secretion inhibitor and to pharmaceutical preparations based on these compounds.