Patent · US Expired

Heterocyclic derivatives

US4585781A · kind A · utility

1Cited by
0References
7Claims
0Family size

Assignee

Inventors

Key dates

Filing dateDec 30, 1983
Grant dateApr 29, 1986
Priority date
Expiry dateDec 30, 2003

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D417/12
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

This invention relates to compounds of the general formula (I) ##STR1## and physiologically acceptable salts and hydrates thereof, in which R.sub.1 represents a hydrogen atom or an alkyl, alkanoyl, aroyl or trifluoroalkyl group; PA0 R.sub.2 represents a hydrogen atom or an alkyl or alkenyl group or C.sub.2-6 alkyl group substituted by a hydroxy or alkoxy group; PA0 X represents a sulphur atom or NH; PA0 Y represents an oxygen or sulphur atom or a bond; PA0 m represents 1, 2 or 3; and PA0 n represents 2, 3 or 4. The compounds show pharmacological activity as selective histamine H.sub.2 -antagonists.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.