Polymerized vesicles and compounds for their preparation
US4587055A · kind A · utility
8Cited by
4References
15Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Jun 8, 1984 |
| Grant date | May 6, 1986 |
| Priority date | — |
| Expiry date | Jun 8, 2004 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07F9/10
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Lower-.omega.-alkenoyloxy-long chain alkanoic anhydrides are synthesized from the .omega.-hydroxyalkanoic acids and are condensed with glycerophosphatidyl cholines to prepare alkenoyloxyalkanoic esters of glycerophosphatidyl cholines. These are used to make vesicles which are then polymerized in situ. These vesicles show improved stability and the rate of leakage of entrapped active ingredients such as drugs can be controlled. They are also used to form a hydrophyllic monolayer on polyethylene.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.