4-alkyl-thiophenyl-ethanolamines, having an activity the cerebral circulation, the blood platelet-aggregation and the lipenia
US4587248A · kind A · utility
1Cited by
1References
16Claims
0Family size
Inventors
Key dates
| Filing date | May 27, 1982 |
| Grant date | May 6, 1986 |
| Priority date | — |
| Expiry date | May 27, 2002 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D295/092
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
4-alkyl-thiophenyl-ethanolamines are disclosed, which are compounds having a therapeutical activity against blood-platelet aggregation, and against lipemia and improving the cerebral circulation, said ethanolamines having the general formula: ##STR1## wherein R and R.sub.1 are alkyl substituents and R.sub.2 is a substituent having an amine character. Due to the presence of two asymmetry centers in their molecule, the compounds concerned can be prepared in the "threo" and the "erythro" configuration: mixtures of the "threo" and the "erythro" forms have also proven effective.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.