Indolo[2,3-a]quinolizine and indolo[2,3-g]cyclopent[a]indolizine derivatives, compositions and methods employing them for treating ulcers
US4587251A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jun 27, 1984 |
| Grant date | May 6, 1986 |
| Priority date | — |
| Expiry date | Jun 27, 2004 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D211/82
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The invention relates to new indolo[2,3-g]cyclopent[a]indolizine derivatives of the formulae (II) ##STR1## and/or (III) ##STR2## wherein W is alkoxycarbonyl having from one to four carbon atoms in the alkoxy moiety or cyano, PA1 R.sub.1 is hydrogen or alkyl having from one to four carbon atoms, PA1 G is a >CH.sub.2 or >C.dbd.O group, and PA1 X and Y each stands for hydrogen or together represent a C--C bond. According to another aspect of the invention there is provided a process for the preparation of the above compounds, which are pharmaceutically active, in particular, possess valuable gastric acid secretion inhibiting activity. Pharmaceutical compositions containing compounds of the formulae (II) and/or (III) are also within the scope of the invention.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.