Process for production of optically active oxazolidinone derivative
US4588694A · kind A · utility
7Cited by
6References
23Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Aug 12, 1983 |
| Grant date | May 13, 1986 |
| Priority date | — |
| Expiry date | Aug 12, 2003 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12P17/14
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A process for preparing the optically active oxazolidinone derivative [(S)-I] by utilizing microorganisms or enzymes having a stereoselective esterase activity capable of asymmetrically hydrolyzing the racemates of the acyloxyoxazolidinone derivative [(R,S)-II], by separating the unreacted compound [(S)-II] from the hydrolyzed compound [(R)-I] and by hydrolyzing the compound [(S)-II]. The compounds are useful as intermediates for preparing optically active .beta.-adrenergic blocking agents.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.