Patent · US Expired

Live vaccine for bovine babesiosis and method of preparation

US4590072A · kind A · utility

2Cited by
0References
4Claims
0Family size

Assignee

Inventors

Key dates

Filing dateOct 31, 1984
Grant dateMay 20, 1986
Priority date—
Expiry dateOct 31, 2004

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61K39/018
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

A live vaccine for bovine babesiosis comprises viable bovine erythrocytes parasitized with a cloned population of Babesia bovis, the clone strain being fast-growing, avirulent, and producing a mild but immunizing infection when administered. The vaccine is free of slow-growing virulent B. bovis. The clone strain used in the vaccine is prepared from a natural mixture of virulent and avirulent babesia by progressive dilution culturing to obtain cultures containing single parasites, propagating the single parasites under favorable conditions for growth, and selecting a fast-growing avirulent clone line for either in vitro or in vivo propagation to prepare the vaccines.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.