Synthetic immunoregulators and methods of use and preparation
US4590181A · kind A · utility
10Cited by
2References
4Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Dec 20, 1982 |
| Grant date | May 20, 1986 |
| Priority date | — |
| Expiry date | Dec 20, 2002 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2039/57
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
To regulate the immune response to an antigen, a subject is injected with the antigen and a polyanionic polysaccharide derivative having a molecular weight of between 10,000 and 600,000 selected to correspond to the antigen. For virus, as an example, mycodextran sulfate or pustulan sulfate may be used in sufficient quantities to stimulate cell-mediated immune responses without stimulating synthesis of gamma E globulin and gamma G globulin. The polyanionic polysaccharide may be injected along to stimulate cell-mediated immune responses to antigens in a diseased subject.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.