Patent · US Expired

Matrix of antibody-coated spots for determination of antigens

US4591570A · kind A · utility

144Cited by
8References
21Claims
0Family size

Assignee

Inventor

Key dates

Filing dateFeb 2, 1983
Grant dateMay 27, 1986
Priority date
Expiry dateFeb 2, 2003

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY10S436/815
  • WIPO fieldMeasurement
  • WIPO sectorInstruments

Abstract

This invention relates to a novel immunoassay device and method for the determination of antigenic substances. The device essentially comprises a pattern or array of minute antibody-coated spots on the surface of a support. The array of antibody-coated spots is preferably in the form of a rectangular matrix. Each antibody-coated spot is made up of antibodies of a different and distinct specificity. A large number of different antibody-coated spots can be assembled on a very small portion of the surface of the support. The spots serve as tiny, specific immunoadsorbents of cells. The expression of particular surface antigen by cells may be detected by determining to which antibody-coated spot the cells bind.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.