1-alkyl-androsta-1,4-diene-3,17-diones their production and pharmaceutical preparations containing same

US4591585A · kind A · utility

Assignee

• SCHERING CORPORATION · US

Inventors

• Ulrich Kerb
• Gerhard Sauer · Berlin, DE
• Rudolf Wiechert · Berlin, DE
• David Henderson · Berlin, DE
• Yukishige Nishino · Berlin, DE
• Sybille Beier · Berlin, DE

Key dates

• Filing date: Jun 18, 1984
• Grant date: May 27, 1986
• Expiry date: Jun 18, 2004

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P35/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

1-Alkyl androsta-1,4-diene-3,17-diones of the formula ##STR1## wherein R.sub.1 is a methyl, ethyl, hydroxymethyl, C.sub.1 -C.sub.3 -alkoxymethyl, or C.sub.1 -C.sub.4 -alkanoyloxymethyl group, R.sub.6 is a hydrogen atom or a methyl group, and R.sub.7 is a hydrogen atom or a methyl group in the 7.alpha.- or 7.beta.-position, are useful for fertility control and for the treatment of estrogen-triggered diseases.