Selective acylation process
US4592869A · kind A · utility
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23Claims
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Assignee
Inventors
Key dates
| Filing date | Sep 28, 1984 |
| Grant date | Jun 3, 1986 |
| Priority date | — |
| Expiry date | Sep 28, 2004 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07J75/00
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
This invention relates to a selective acylation process for the preparation of phenolic N-disubstituted carbamate esters of steroids, comprising reacting in an inert solvent an acylating agent being a carbamoyl halogenide, a 4-(tertiary amino)-pyridine, or a complex thereof, optionally as a part of a polymer and a steroid having at least two free hydroxy groups, where at least one is phenolic and at least one is alcoholic, optionally in the presence of an acid acceptor.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.