Antigenic materials
US4594244A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Feb 10, 1984 |
| Grant date | Jun 10, 1986 |
| Priority date | — |
| Expiry date | Feb 10, 2004 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S530/825
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
An antigenic material having a molecular weight of 3800-4500, and useful in the preparation of an anticaries vaccine is produced from a known antigenic material, antigen I/II of molecular weight 185,000 daltons obtained from the culture supernatant of Streptococcus mutans. The smaller molecular weight fraction of the invention contains the same antigenic determinants as the known 185,000 dalton material but the lower molecular weight material can be used with less side effects. The antigenic material can be used for the production of vaccine preparations that could be administered parenterally or by topical application to the gums.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.