Patent · US Expired

Method and apparatus for sample retrieval from pharmaceutical dissolution testers

US4594902A · kind A · utility

6Cited by
8References
8Claims
0Family size

Assignee

Inventors

Key dates

Filing dateAug 23, 1985
Grant dateJun 17, 1986
Priority date—
Expiry dateAug 23, 2005

Classification

  • Technology area (CPC G)Physics
  • CPC primaryG01N2035/1006
  • WIPO fieldMeasurement
  • WIPO sectorInstruments

Abstract

Discrete robotic sampling apparatus for withdrawing samples of pharmaceutical formulations having particulates therein contained within a plurality of dissolution vessels. The apparatus employs a single sampling probe utilizing a single in-line filter therein. Movement of the probe is guided by a robotic arm controlled by a programmable microprocessor which also controls a reversible pump for flushing the particulates retained by the filter, by means of filtered sample, back into the dissolution vessel, prior to dispensing a portion of the filtered sample into a sample container. The probe is then programmed to be washed with a wash solution prior to inserting of the probe into another dissolution vessel for withdrawing of sample therefrom.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.