Preparation of penem derivatives and azetidinone intermediates
US4595539A · kind A · utility
3Cited by
9References
10Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Jun 10, 1983 |
| Grant date | Jun 17, 1986 |
| Priority date | — |
| Expiry date | Jun 10, 2003 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D499/88
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Certain 2-substituted-2-penem-3-carboxylic acid compounds and pharmaceutically-acceptable salts thereof can be prepared from the appropriate xanthate or trithiocarbonate by desulfurization and addition of an electrophilic sulfur compound followed by halogenation and ring closure. The corresponding desulfurized and halogenated olefinic intermediates are disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.