2-acetylpyridine thiosemicarbazones as antiviral agents

US4596798A · kind A · utility

Assignee

• The United States of America as represented by the Secretary of the Army · US

Inventors

• Charles Shipman, Jr. · Dexter, US
• Daniel L. Klayman · Bethesda, US
• Sandra H. Smith · Ann Arbor, US
• John C. Drach · Ann Arbor, US

Key dates

• Filing date: Mar 30, 1982
• Grant date: Jun 24, 1986
• Expiry date: Mar 30, 2002

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K31/44
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

This invention relates to the use of various 2-acetylpyridine thiosemicarbazones which are substituted on the 4-nitrogen atom in the treatment of viral infections. Also disclosed are several synthetic procedures used to prepare the thiosemicarbazones.