Method for quantitatively assaying blood coagulation factor XII in human plasma
US4598043A · kind A · utility
22Cited by
10References
6Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Oct 28, 1982 |
| Grant date | Jul 1, 1986 |
| Priority date | — |
| Expiry date | Oct 28, 2002 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2333/96458
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A method for assaying blood coagulation factor XII in human blood plasma wherein plasma is treated with an activator in order to convert factor XII present in the plasma into factor XIIa, the latter is reacted with a tripeptide derivative which is split by the enzymatic action of factor XIIa and forms a colored or fluorescent split product, and the quantity of this split product is measured photometrically, spectrophotometrically or fluorescence-spectrophotometrically.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.