Optically active derivatives of N-arylated oxazolidine-2-one, the process for preparing same and their application in therapeutics

US4598084A · kind A · utility

Assignee

• Delalande S.A. · FR

Inventors

• Margherita Strolin-Benedetti · Paris, FR
• Patrick G. Guerret · Rueil-Malmaison, FR
• Michel Langlois · Buc, FR
• Philippe L. Dostert · Chaville, FR

Key dates

• Filing date: Jun 3, 1983
• Grant date: Jul 1, 1986
• Expiry date: Jun 3, 2003

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D317/28
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

N-arylated oxazolidine-2-one derivatives corresponding to the formula: ##STR1## and of S(+) configuration, A representing in this case the hydroxyl radical or of R (+) configuration, A designating then the N-methylamino group, as well as the acid addition salts thereof. Application in therapeutics more particularly as monoamine oxidase inhibitors.