Gonadoliberin derivatives containing a .beta.-aspartyl group, a process for the preparation thereof and pharmaceutical preparations containing them
US4600705A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Mar 29, 1984 |
| Grant date | Jul 15, 1986 |
| Priority date | — |
| Expiry date | Mar 29, 2004 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S930/13
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to novel gonadoliberine derivatives of the general formula (I) ##STR1## wherein X represents an --O--R group wherein R is a benzyl group or a C.sub.1-4 alkyl group, an ##STR2## group wherein R1 and R2 independently stand for hydrogen, a C.sub.1-5 alkyl, aryl, aryl-C.sub.1-2 -alkyl, morpholino, 1-indolinyl or 1-pyrrolidinyl group, PA1 Y is a glycine amide or a C.sub.1-4 -alkyl-amide group, the addition salts thereof formed with acids used in therapy and complexes thereof as well as pharmaceutical compositions containing them, furthermore to a process for the preparation of the above compounds. The reproductive processes of vertebrates can be advantageously influenced with the compounds of general formula (I).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.