Patent · US Expired

Benzodioxole derivatives, processes for the manufacture thereof and corresponding pharmaceutical compositions

US4600709A · kind A · utility

2Cited by
3References
21Claims
0Family size

Assignee

Inventors

Key dates

Filing dateDec 7, 1984
Grant dateJul 15, 1986
Priority date
Expiry dateDec 7, 2004

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D417/12
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

The invention relates to novel benzodioxole derivatives of the general formula I ##STR1## in which R.sub.1 represents an unsubstituted or substituted, aliphatic, aromatic or heteroaromatic radical, PA1 alk represents an alkylene, alkenylene or alkylidene radical having a maximum of 5 carbon atoms, PA1 n.sub.1 represents 0, 1 or 2 PA1 n.sub.2 represents 0 or 1, PA1 R.sub.2, R.sub.3 and R.sub.4 each represents, independently of the others, hydrogen, lower alkyl, lower alkoxy or halogen, and PA1 A represents the radical --O--R.sub.5, wherein R.sub.5 represents hydrogen or an unsubstituted or substituted, aliphatic or araliphatic hydrocarbon radical, or A represents the radical ##STR2## in which either R.sub.6 and R.sub.7 each represents, independently of the other, hydrogen or lower alkyl, or R.sub.6 and R.sub.7 are bonded to one another and, together with the adjacent nitrogen atom, represent optionally lower alkyl-substituted tetra- to hexa-methyleneimino, 4-morpholinyl or 1H-tetrazol-1-yl, such as, for example, 5-methyl-6-phenylsulphonyl-1,3-benzodioxole-2-carboxylic acid. The invention relates also to salts of compounds of the general formula I in which A represents OR.sub.5 where…

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.